Engineering Precise Control of Cellular Motion

The Buffone Cellular Motion Lab is based in the Biomedical Engineering department at the New Jersey Institute of Technology. Our research lies at the intersection of Glycobiology, Cell Migration, Mechanobiology, and Engineering. Our lab utilizes a combination of CRISPR genetic engineering, microfludics, and models of acute inflammation, we study how both cancer and immune cells interact and move in their environment. By disrupting the cell surface, mechanosensitive receptors, and glycocalyx composition, our ultimate goal is to fine-tune and precisely control cell migration for therapeutic benefit during disease states.